Haijun Xiao

Pure drug Nanoparticle systems for Theranostics (Pharmacotherapy, PTT, PDT), Bioimaging (NIR, X-ray), Light conversion and so on.

Ultrasound-mediated controlled drug delivery.

Xiao H, Li Q. A multi-ring self-dispersing particle system, its preparation method, preparation device, and application. (2023, CN)

Xiao H, A turmeric self-dispersing particle system, preparation therefor and application thereof. (2022, CN)

Xiao H, Li Q. A golden nanpparticle system, preparation therefor and application thereof. (2021, CN)

Xiao H. A self-dispersing particle system, preparation therefor and application thereof. (2021, CN, 2022 PCT)

Xiao H, Sedlařík V. Preparation and formulation of nanoparticles with enhanced biological availability for use in anticancer therapy. (2018, WO)

Xiao H, Shrestha B, Gallegos G, Kalensky N, Patel D, Bocchetta M, Porter T, Aryal M. The efficiency of ultrasonic glymphatic manipulation-based intrathecal drug delivery depends on the physiological states. (To be submited)

Xiao H, Fei H, Zhang M, Zhao W, Li Q, Li C. A Universal Approach to Aqueous Nano: Charge Balanced Aggregation of Conjugated Molecules. (To be submited)

Xiao H, Guo Y, Liu H, Liu Y, Wang Y, Li C, Císař J, Škoda D, Kuřitka I, Guo L, Sedlařík V. Structure-based design of charge-conversional drug self-delivery systems for better targeted cancer therapy. (Biomaterials. 2020 Feb;232:119701, IF 12.479)

Guo Y, Liu H, Xiao H, Yuan M, Liu Y, Sedlařík V, Chin WC, Liu J, Guo L, Li C. Self-assembled Camptothecin derivatives - Curcuminoids conjugate for combinatorial chemo-photodynamic therapy to enhance anti-tumor efficacy. (J Photochem Photobiol B. 2021 Feb;215:112124, IF 6.252)

Xiao H, Sedlařík V. A Rapid and Sensitive HPLC Method for Simultaneous Determination of Irinotecan Hydrochloride and Curcumin in Co-delivered Polymeric Nanoparticles. (J Chromatogr Sci. 2020 Jul 24;58(7):651-660, IF 1.618)

Xiao H, Wang L. Effects of X-shaped reduction-sensitive amphiphilic block copolymer on drug delivery. (Int J Nanomedicine. 2015 Aug 24;10:5309-25, IF 6.4)

Liu H, Yuan M, Liu Y, Guo Y, Xiao H, Guo L, Liu F. Self-Monitoring and Self-Delivery of Self-Assembled Fluorescent Nanoparticles in Cancer Therapy. (Int J Nanomedicine. 2021 Mar 29;16:2487-2499, IF 6.4)

Postdoc Fellow at Department of Radology, University of Michigan (Ann arbor)

Conducted research on ultrasound-mediated controlled drug delivery.

Postdoc Fellow at Engineering and Radiation Oncology, Loyola University Chicago

Conducted research on ultrasound-mediated intrathecal drug delivery for the treatment of brain metastatic cancer.

Academic Researcher at Centre of Polymer Systems, Tomas Bata University

Conducted research on self-delivered nano-systems for bio applications.

Ph.D. in Material Science and Engineering, Tomas Bata University

Research emphases: Novel Drug Delivery Systems for Cancer Therapy

M.S. in Chinese Medicinal Science, University of Macau

Research emphases: Molecular Pharmaceutics, Targeted Drug Delivery, Biosafety Evaluation (GPA: 3.25 / 4.0)

B.S. in Pharmaceutics, China Pharmaceutical University

Study emphases: Pharmaceutics, Pharmaceutical Analysis, Medicinal Chemistry, Pharmacology (GPA: 3.44 / 4.0)

Academic Visitor at Qingdao Agricultural University, China. "A drug self-delivery system for myocardial ischemia protection on nude mice".

Academic Visitor at University of California, Merced. "A drug self-delivery system for cancer treatment based on photodynamic therapy".

"HR Mobility" – Research experience in Chengdu University of TCM, China. In vivo therapeutic effects of anti-cancer drugs on nude mice.

Invited Oral Presentation at "Bioengineering seminar series", with topic "Drug self-delivery systems for cancer therapy" (California, U.S.).

Oral Presentation at conference "Poly-Char World Forum on Advanced Materials", with topic "A drug self-delivery system for cancer therapy" (Naples, Italy).

Oral Presentation at conference "NewGen Conference: Hydrogel/Bio-mineralised Biomaterial", with topic "Polymeric micellar nano systems for drug delivery" (Zlin, Czech Republic)

Funded by Internal Grant Agency. IGA/CPS/2017/005; IGA/CPS/2018/003; IGA/CPS/2019/006; IGA/CPS/2020/002.

Funded by Ministry of Education, Youth and Sports of the Czech Republic

Design of pure drug nanoparticle systems for multiple applicaitons.

Pharmaceutical Preparation and Characterisation (DLS, PL, SEM, HPLC, XRD, etc.)

in vitro and in vivo Evaluation (Biosafety, Delivery efficiency and Drug efficacy) on Rats and Mice.

R programming for data analysis.

Design of Stereotaxic Devices for Rodents.

English (Professional working proficiency)